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Burcak Karaca Selected Research

calyculin A

3/2016Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway.
12/2012Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone-refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A.

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Burcak Karaca Research Topics

Disease

9Breast Neoplasms (Breast Cancer)
01/2020 - 10/2009
9Neoplasms (Cancer)
01/2020 - 10/2009
9Prostatic Neoplasms (Prostate Cancer)
04/2016 - 09/2008
3Carcinoma (Carcinomatosis)
01/2019 - 12/2008
3Neoplasm Metastasis (Metastasis)
01/2014 - 12/2012
3Ovarian Neoplasms (Ovarian Cancer)
06/2013 - 09/2009
2Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2016 - 08/2015
2Colorectal Neoplasms (Colorectal Cancer)
01/2014 - 08/2013
2Disease Progression
01/2014 - 08/2013
1Melanoma (Melanoma, Malignant)
01/2022
1Lymphadenopathy
01/2022
1Squamous Cell Carcinoma of Head and Neck
01/2019
1Aggressive Fibromatosis (Desmoid)
01/2016
1Fatigue
10/2015
1Neutropenia
10/2015
1Febrile Neutropenia
10/2015
1Triple Negative Breast Neoplasms
01/2015
1Peritoneal Fibrosis
05/2011
1Bone Diseases (Bone Disease)
07/2010

Drug/Important Bio-Agent (IBA)

10Hormones (Hormone)IBA
04/2016 - 09/2008
9Pharmaceutical PreparationsIBA
04/2016 - 09/2008
7Zoledronic Acid (Zometa)FDA Link
03/2016 - 09/2009
7Docetaxel (Taxotere)FDA Link
02/2016 - 09/2008
5gossypol acetic acidIBA
01/2020 - 10/2010
4GossypolIBA
10/2010 - 12/2008
3Octreotide (Sandostatin)FDA LinkGeneric
04/2016 - 07/2009
3Proteins (Proteins, Gene)FDA Link
06/2013 - 07/2012
3Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2011 - 09/2008
2PlatinumIBA
01/2019 - 06/2013
2Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
03/2016 - 12/2012
2Okadaic AcidIBA
03/2016 - 12/2012
2Serine (L-Serine)FDA Link
03/2016 - 12/2012
2Threonine (L-Threonine)FDA Link
03/2016 - 12/2012
2calyculin AIBA
03/2016 - 12/2012
2Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
06/2015 - 07/2009
2EnzymesIBA
02/2015 - 06/2013
2Biological ProductsIBA
01/2015 - 12/2008
2Bevacizumab (Avastin)FDA Link
01/2014 - 08/2013
2thiamine triphosphorate (TTP)IBA
01/2014 - 08/2013
2Messenger RNA (mRNA)IBA
06/2013 - 09/2009
2AndrogensIBA
12/2012 - 01/2011
2Cytotoxins (Cytolysins)IBA
12/2012 - 01/2011
2Diphosphonates (Bisphosphonates)IBA
12/2012 - 07/2010
2Antineoplastic Agents (Antineoplastics)IBA
07/2010 - 09/2008
1Immune Checkpoint InhibitorsIBA
01/2022
1Trastuzumab (Herceptin)FDA Link
01/2020
1Fluorouracil (Carac)FDA LinkGeneric
01/2019
1Cetuximab (Erbitux)FDA Link
01/2019
1somatostatin receptor 2IBA
04/2016
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
03/2016
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
02/2016
1pazopanibFDA Link
01/2016
1ErbB Receptors (EGF Receptor)IBA
10/2015
1Capecitabine (Xeloda)FDA Link
10/2015
1Cytochromes c (Cytochrome c)IBA
06/2015
1Apoptosis Regulatory ProteinsIBA
06/2015
1Caspase 3 (Caspase-3)IBA
02/2015
1thymoquinoneIBA
10/2014
1TrabectedinIBA
08/2013
1Oxaliplatin (Eloxatin)FDA LinkGeneric
08/2013
1Irinotecan (Camptosar)FDA LinkGeneric
08/2013
1MethyltransferasesIBA
06/2013
1Histone Deacetylases (Histone Deacetylase)IBA
06/2013
1DNA (Deoxyribonucleic Acid)IBA
06/2013
1Cisplatin (Platino)FDA LinkGeneric
06/2013
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
12/2012
1Death Domain ReceptorsIBA
07/2012
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2012
1LigandsIBA
07/2012
1Histones (Histone)IBA
01/2012
1Angiogenesis InhibitorsIBA
05/2011
1Sunitinib (Sutent)FDA Link
05/2011
1resazurinIBA
10/2010
1Insulin (Novolin)FDA Link
10/2009
1Metformin (Glucophage)FDA LinkGeneric
10/2009
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2009
1CytokinesIBA
12/2008
1SurvivinIBA
09/2008

Therapy/Procedure

7Drug Therapy (Chemotherapy)
01/2019 - 10/2009
5Therapeutics
10/2015 - 10/2009
2Adjuvant Chemotherapy
02/2016 - 08/2015
2Combination Drug Therapy (Combination Chemotherapy)
01/2014 - 08/2013
1Immunotherapy
01/2022
1Aftercare (After-Treatment)
12/2008